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In contrast to the above, the dysregulation of mTOR signaling triggers the abnormal metabolism of protein, causative of tumor cell persistence and drug challenge, as demonstrated in research investigating the effects of mTOR inhibitors in several tumor models, including renal adenocarcinoma (96)

2026;14(2):e70340

Clinical trials on the treatment of chronic OIPN: study characteristics and main outcomes

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Further, it has been used to treat many cardiovascular, reproductive, central nervous systems, inflammatory disorders, osteoarthritis, rheumatoid arthritis, and fungal and bacterial infections