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Substantially, actions of anti-inflammation, oxidative stress and apoptosis produced by artemisinin and its derivatives were found throughout the three phases, and NF-B, Keap1/Nrf2 and PI3K/Akt may be the key signaling pathways

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To determine whether inhibition of G6PD activity by influenza virus infection involved post-translational mechanisms other than antioxidant gene regulation, we next evaluated the role of SIRT2 in regulating G6PD dimer formation, based on previous studies demonstrating that deacetylation of G6PD at Lys403 stimulated dimer formation and consequently the G6PD activity (Wang et al., 2014)

Clinical features of non-alcoholic fatty liver disease in the non-lean population

CagianelliMAAndreiniRet al