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For visualization, we generated stacked bar plots showing the proportions of upregulated, downregulated, and non-significant neighborhoods per cell type in each condition

Previous studies have shown that SASP could significantly reduce the Mtb bactericidal load and histopathological inflammation of lungs in mice, and prevent severe inflammation induced by Mtb infection of human macrophages (Cai et al., 2016

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The detailed composition and dosage of each ingredient in the Amino Liver formulation and the placebo are provided in Supplementary Table S1