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Furthermore, in mice with an Hfe gene knockout, elevated levels of malondialdehyde (MDA) were observed in colonic tissues, and iron overload promoted oxidative damage in colon cells

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doi: 10.1016/j.plaphy.2011.12.00

We employ a gradient descent algorithm to minimize the Mean Squared Error (MSE) loss function defined over the simulation duration: where the sum runs over all discrete time steps t k of the simulation

Animals treated with EAE exhibited stimulation of a few proliferation factors through increase of the height of the epithelial regeneration area and expression of PCNA in the nucleus