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Description

In the SURMOUNT-5 trial (NEJM, 2025), tirzepatide reduced body weight by 20.2% versus 13.7% for semaglutide over 72 weeks

Elghaba, R

doi: 10.1007/s40265-024-02134-0 129 GaoA.KouznetsovaV

Partial peripheral nerve injury promotes a selective loss of GABAergic inhibition in the superficial dorsal horn of the spinal cord

These outcomes were accompanied by the restoration of neurotransmitter balance, particularly the enhancement of GABAergic inhibition and the reduction of excessive glutamatergic excitation