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Metabolism of esters by Streptomyces nitrificans

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According to clinical research parenteral administration (intramuscular or intravenous) is preferred over other drug administration routes in case of emergency situations as it provides first-pass metabolism avoidance, reliable therapeutic concentrations and better bioavailability of dosage (2) It can also be used in situations when oral route is not feasible

3.3.2 Excitatory amino acid transporters Glutamate uptake is accomplished in the CNS by excitatory amino acid transporters (EAATs) that are present in the pre- and postsynaptic cell surface of neurons and astrocytes, where glutamate is preferentially recycled (163)

Hydroxocobalamin as a cyanide antidote: safety, efficacy and pharmacokinetics in heavily smoking normal volunteers J Toxicol Clin 1993