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Inhibition of ZIP14 in liver TFR-specific knockout mice ameliorated ferroptosis-mediated liver fibrosis[144]

The highly selective permeability of the BBB largely depends on the presence of continuous TJs that connect ECs, and so it follows that dysregulation of the expression of TJ proteins, such as occludin, claudin-5 and ZO-1, can critically influence BBB permeability

Supramolecular deferoxamine-crisaborole nanoparticle targets ferroptosis, inflammation, and oxidative stress in the treatment of retinal ischemia/reperfusion injury

Disclosures: Naoto Kawabe: Nothing to Disclose, Teiji Kuzuya: Chugai Pharmaceutical Co: Speaking and Teaching, Eisai: Speaking and Teaching, Eli Lilly Japan: Speaking and Teaching, AstraZeneca: Speaking and Teaching, Yoshiki Hirooka: Nothing to Disclose 2614 SAFETY AND EFFICACY OF NAFAMOSTAT MESYLATE ANTICOAGULATION IN CENTRIFUGAL ARTIFICIAL LIVER SUPPORT SYSTEM FOR ALF AND ACLF PATIENTS AT HIGH RISK OF BLEEDING Zhu Xinfang 1 Bing-Yao Wang 1 Jian-Ming Zheng 1 Rong Xia 1 , 1 Huashan Hospital, Fudan University Background: Patients with acute liver failure (ALF) and acute-on-chronic liver failure (ACLF) are consistently at high risk of bleeding and most exhibit decreased platelet levels, presenting a challenge for the conventional approach to artificial liver support systems (ALSS)

Cancer Chemother Pharmacol.2010 May;65(6):1117-2 209