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Grade A evidence includes multi-center cohort studies and meta-analyses with large sample sizes providing the strongest evidence base (81)

7.24.18 Gladys Chong said: Hi

Goday A, Bellido D, Sajoux I, Crujeiras AB, Burguera B, Garca-Luna PP, et al

doi: 10.1186/s40364-024-00622-9 100 ZhouJWangLPengCPengF

These findings shed light on the role of innate enteric immunity in regulating the intestinal microbiota fulfilled by Paneth cell -defensin in the early-life period, with a relatively limited immune system when adaptive immunity, with the exception of IgA, remains immature