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They study authors wrote: Neuropsychiatric symptoms are a well-described side effect of systemic corticosteroid therapy and can range from mild to severe. In this case including psychosis

PMID 16314912

This promoter is active in neural crest cells, and driving MYCN overexpression in these progenitor cells of NB causes the animals (Th- MYCN ) to develop tumors that closely resemble human NB (43)

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Nucleic Acids Research 53:D998D1005