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229 In osteoporosis, MSCs tend to favor adipogenic differentiation, which reduces bone formation and increases fat accumulation within the bone marrow, thereby exacerbating bone loss and increasing the risk of fractures

It has also been found that Keap1/Nrf2 mutation status predicts the risk of local recurrence after radiotherapy in NSCLC patients, and Keap1/Nrf2 mutant lung cancers may be radiotherapy resistant to radaition due to enhanced expression of ROS clearance and detoxification pathways (Umamaheswari et al., 2021)

Vitamin Deficiency It can become difficult to get the vitamins and minerals you need during pregnancy, even when you take supplements

Reduced stress defense in heme oxygenase 1-deficient cells

Another research found that through a randomized controlled study (Fig