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We found that, mechanistically, DON exposure blocks glycolysis and lactate production in porcine granulosa cells, reduces the level of H3K18la, inhibits the expression of STEAP3, leading to an increase in intracellular ferrous ions, thus inducing ferroptosis

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Mammalian organisms, including humans, have evolved the ability to eliminate HTL and one such mechanism involves paraoxonase 1 (PON1), a high-density lipid (HDL) associated protein

RB&E 23 (1), 49

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