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In vivo studies have further demonstrated that PDA NPs can alleviate puncture-induced disc degeneration by suppressing ferroptosis and restoring antioxidant defenses, offering a novel therapeutic strategy for IDD that directly targets ferroptosis-related damage at the mitochondrial level (94,95)

Conclusion: Overall, this study demonstrated that PFOS was unable to promote ALD, unlike our previous model

10.1038/s41422-019-0263-3 70 LeiP.BaiT.SunY

To test this hypothesis, we used in vitro systems

Abstract Mitochondria are essential for cellular function and viability, serving as central hubs of metabolism and signaling