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(2022)reported that treating a PCOS-IR rat model established by letrozole combined with a high-fat diet with Modified CFD can regulate the NF-B/LCN-2 inflammatory signaling pathway, thereby inhibiting the release of inflammatory factors and upregulating insulin signal-related genes, and ultimately improving the insulin sensitivity of PCOS-IR rats

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It is recommended to reconstitute the lyophilized protein in sterile buffered saline to a concentration of no less than 100 g/ml

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Studies have shown that several active compounds found in TCM, such as flavonoids [85], polyphenols [86], and saponins [87], can modulate ovarian function through multiple mechanisms, improving the ovarian microenvironment, promoting follicular development, and enhancing oocyte quality