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Figure 7 Current research on ferroptosis in kidney diseases has predominantly focused on AKI and CKD, with accumulating evidence linking ferroptosis to interstitial fibrosis, mitochondrial dysfunction, inflammatory cell infiltration, and impaired tubular regeneration, key drivers of CKD progression (285, 286)

The realization of T2D as downstream disease of MDS suggests that metabolic complications or MDS-related TOD may be more reasonable instead of so-called chronic diabetic complications

Thus, the mechanisms of MDD development involve the interaction of many components of biological origin, including the microbiota and gut-brain axis

Table of Contents Introduction The digestive system is home to the gastrointestinal (GI) tract where food is being digested and being transformed into nutrients for the body to utilize

Furthermore, accumulating evidence has shown that NNMT knockdown significantly decreases tumorigenesis and chemoresistance capacity