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A cross-sectional study analyzed the data from data from the National Health and Nutrition Examination Survey for 3,675 participants (aged 60 and older) to investigate relationships between dietary flavonoids and stroke risk, the results suggesting that flavonoid-rich dietary patterns are protective against stroke in older adults (56)

Cellular injury induced by oxidative stress is mediated through lysosomal damage

Glutathione peroxidase 4 has a major role in protecting mitochondria from oxidative damage and maintaining oxidative phosphorylation complexes in gut epithelial cells

Copper-dependent toxicity in SH-SY5Y neuroblastoma cells involves mitochondrial damage

According to the literature, the autosomal recessive inheritance pattern is generally associated with a more severe clinical phenotype compared to autosomal dominant cases [38]