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Our typical stem-cell patient has Osteoarthritis (hip dysplasia, degenerative joint disease, calcifications, common degeneration, and inflammation) Soft tissue injuries (cruciate injuries, tears, ruptures, inflammation), or Needs accelerated healing of fractures

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Spatial transcriptomics of archived FFPE biopsies identifies pre-treatment signatures associated with VDZ response and non-response To examine tissue level differences between VDZ responders (VDZ-R) and non-responders (VDZ-NR), we retrieved longitudinal archived FFPE biopsies before and after therapy and performed 1000-plex CosMx spatial transcriptomics (Fig