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Higher expression of Wnt1 in epidermal cells of melasma compared to normal control tissue has also been reported [25]

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In summary, PCBPs may provide strategies for the efficient management of the newly acquired or mobilized iron atoms by efficiently delivering them to their appropriate destination, particularly in cell types that routinely encounter dynamic changes in the cytosolic LIP

Ultimately, the gut microbiota can now be regarded as a crucial distal regulator of OA pathogenesis in many ways including regulation of the intestinal barrier function, effect on immune-inflammatory mechanisms and regulation of host metabolic disorders

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