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For example, halogenated cysteine S-conjugates can generate highly reactive thiol-containing fragments through the action of cysteine S-conjugate b-lyases: where RSH is the thiol form of the xenobiotic, which can be toxic

Oxidative stress and mitochondrial function are relevant to energy and ageing biology

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This can affect the normal physiological functions of proteins and contribute to aging-related complications

Varderidou-Minasian S, Verheijen BM, Schtzle P, Hoogenraad CC, Pasterkamp RJ, Altelaar M (2020) Deciphering the proteome dynamics during development of neurons derived from induced pluripotent stem cells