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Synergistic ferroptosis in triple-negative breast cancer cells: paclitaxel in combination with Erastin induced oxidative stress and Ferroportin-1 modulation in MDA-MB-231 cells

doi: 10.1186/s13293-024-00630-2 96 QinYWangYZhaoHYangZKangY

Mitochondrial fission or mitochondrial fusion A process by which mitochondria are combined (fusion) or divided into smaller fragments (fission)

Recent research found that Kaempferol suppresses CCl-induced liver fibrosis progression by restoring GM diversity, reducing the relative abundance of Faecalibaculum and Bifidobacterium, while increasing that of Lactobacillus, Bacteroides, and Allobaculum, and elevating SCFAs levels in the gut and liver, thereby activating the Nrf2 signaling pathway to reduce oxidative damage [234]

To evaluate the potential for transitivity, the distribution of the potential effect modifiers across the available direct comparisons was assessed