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DOI: 10.1073/pnas.1412944111 Oh, D.Y., Walenta, E., Akiyama, T.E., Lagakos, W.S., Lackey, D., Pessentheiner, A.R., Sasik, R., Hah, N., Chi, T.J., Cox, J.M., Powels, M.A., Di Salvo, J., Sinz, C., Watkins, S.M., Armando, A.M., Chung, H., Evans, R.M., Quehenberger, O., McNelis, J., Bogner-Strauss, J.G., Olefsky, J.M

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Moreover, there are other factors with less mutations and frequency including BRAF, MYC, KRAS, RB1 and SMAD4