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Wautier JL, Guillausseau PJ

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Salehi, B., Venditti, A., Sharifi-Rad, M., Krgiel, D., Sharifi-Rad, J., Durazzo, A., Lucarini, M., Santini, A., Souto, E

[39] The elderly are at increased risk because they tend to produce less stomach acid as they age, a condition known as achlorhydria, thereby increasing their probability of B 12 deficiency due to reduced absorption

The nanoencapsulation of plant extracts rich in polyphenols (such as flavonoids and chlorogenic acid) in alginate and gelatin nanoparticles increased the systemic bioavailability of antioxidants by about 40%