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In another further embodiment of any of the foregoing, the toothpaste formulation includes at least seven of: Spirulina/IMMULINA

doi:10.1016/j.freeradbiomed.2024.01.005

IGF-1 LR3 (-1 3) 1, IGF-1 LR3 (-1 3) ,

This lactylation augments the transcriptional activity of the downstream gene LINC01127, thereby enhancing the self-renewal and detrimental cancer progression of GBM cells through the MAP4K4/JNK/NF-B axis (155)