vitamin b12 injections constipation Do Supplements Make You Constipated? Vitamin B12 deficiency: Causes, symptoms,

2 Serum uric acid levels are typically considered elevated when they exceed ~7.0 mg/dL in men and 6.0 mg/dL in women

If you are B12-deficient, your doctor will determine how much of the vitamin you need to take

hospitalization required Maintenance of Remission: Immunomodulators (azathioprine, 6-MP, methotrexate) for steroid-dependent or frequently-relapsing disease Biologic monotherapy or combination therapy (biologic + immunomodulator) for moderate-to-severe disease Step-up or top-down approach based on disease severity, patient risk factors, and prior therapy Biologic Therapy Targets: TNF-: Infliximab (IV), adalimumab (SC), certolizumab pegol (SC) IL-12/23: Ustekinumab (IV induction, SC maintenance) Integrin: Vedolizumab (IV) IL-23: Risankizumab (IV induction, SC maintenance) JAK inhibition: Upadacitinib (oral) Surgical Management Surgery is indicated in approximately 7080% of patients with Crohns disease over their lifetime, per StatPearls

Medically reviewed by: Micheal Seay, MSN, APRN, FNP-BC

Regulation of cholesterol and fatty acid synthesis