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doi: 10.1097/FJC.0000000000001654 92

1.4 Glucocorticoid-Induced Osteoporosis Reclast is indicated for the treatment and prevention of glucocorticoid-induced osteoporosis in men and women who are either initiating or continuing systemic glucocorticoids in a daily dosage equivalent to 7.5 mg or greater of prednisone and who are expected to remain on glucocorticoids for at least 12 months [see Clinical Studies (14.4)]

Beyond TB-500, BPC-157 is sometimes considered alongside hormone optimization, since both support tissue integrity and recovery at a foundational level

Its also known that nerve damage is generally caused by several factors at the same time

Acute discontinuation syndrome from dexmedetomidine after protracted use in a pediatric patient