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Most other NCEs under investigation follow traditional therapeutic avenues explored for uterine fibroids, which signals limited innovation: there are three GnRH antagonists, including merigolix (Phase II), and a selective progesterone receptor antagonist, telapristone, currently investigated in a Phase II study as a vaginal insert (both also investigated for endometriosis-related pain)

This is a trial starting dose, not an approved patient dose

Common Anxiety Symptoms Anxiety can cause a range of symptoms that can be physical, and some may be emotional

J Thorac Cardiovasc Surg 158(3):924-929, 2019

Frequently reported side effects are nausea, vomiting and diarrhoea