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NNMT Inhibition Mechanism and Optimal Dosing Range 5-Amino-1MQ functions as a small-molecule competitive inhibitor of nicotinamide N-methyltransferase (NNMT), the enzyme responsible for methylating nicotinamide

SAM radiolabeled S-adenosyl-L-[methyl-3H]methionine a radiometric assay was performed by RBC using 1 M-50 pM tolcapone as an inhibitor positive control

Identification of NAPRT inhibitors with anti-cancer properties by in silico drug discovery

one small human study found that taking a dandelion supplement increased the amount of urine produced in the five hours after taking the supplement (2017)