glutathione-responsive prodrug

glutathione-responsive prodrug GSH-triggered drug release and the responsive mechanism of Construction of glutathione-responsive paclitaxel prodrug

Name: glutathione-responsive prodrug GSH-triggered drug release and the responsive mechanism of Construction of glutathione-responsive paclitaxel prodrug
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SKU: 85438404997
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Construction of glutathione responsive paclitaxel prodrug nanoparticles for image guided targeted delivery and breast cancer therapy RSC Advances (RSC Publishing) DOI:10.1039 D4RA00610K PDF) Glutathione responsive iNOS inhibiting polymeric prodrug for targeted Inhibition of angiogenesis Glutathione Responsive Prodrug Nanoparticles for Effective Drug Delivery and Cancer Therapy ACS Nano Activatable theranostic prodrug scaffold with tunable drug release rate for sequential photodynamic and chemotherapy Wang 2024 Smart Molecules Wiley Online Library Emerging Strategies in Stimuli Responsive Prodrug Nanosystems for Cancer Therapy ACS Nano

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Description

Kheirouri S, Alizadeh M

Taking advantage of the fact that they can be reduced by thiols that exist in the cell cytoplasm, such as glutathione, ADCs have been engineered to be conjugated to the disulfide linkers that remain stable in the circulation and selectively release drugs in the cytoplasm