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Genetic screens, as well as studying the evolution of increased antibiotic tolerance in bacteria, have revealed that the tolerome, that is, the genes linked to increased tolerance, is extremely large 32,33

Nat Biotechnol 42:293304 Harigae H, Takahashi S, Suwabe N, Ohtsu H, Gu L, Yang Z, Tsai FY, Kitamura Y, Engel JD, Yamamoto M (1998) Differential roles of GATA-1 and GATA-2 in growth and differentiation of mast cells