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Owing to their diverse etiologies, onset ages, and potential repair mechanisms, the discovery of new treatments for treating myelin pathologies should aim at globally stimulating endogenous oligodendrogenesis, known to spontaneously increase following injury, at multiple levels, i.e., from the specification of new OPCs from neural progenitor cells (NPCs), to the maturation of pre-existing ones within the parenchyma

The other authors report no conflicts

Retatrutide is an investigational medication currently being studied in clinical trials and is not FDA-approved for routine prescribing or compounding

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