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Hiroyuki Itokawa showing its ability to inhibit tumor growth, disrupt angiogenesis (the formation of new blood vessels that feed tumors), and induce apoptosis (programmed cell death) in cancer cells

A recent double-blind, placebo-controlled randomized trial showed beneficial effects of the consumption of 2 cps/day, for two months, of an oral food supplement (OFS), based on Echinacea angustifolia, rosehip, propolis, royal jelly, and zinc, in LC patients

Mol Cell Biochem 220:117125 Brown LJ LM, Hasan NM, Kendrick MA, Stoker SW, MacDonald MJ (2009) Chronic reduction of the cytosolic or NAD(P)-mitochondrial malic enzymes does not affect insulin secretion in a rat insulinoma cell line

Although more large trials are needed, the existing data underline its role in brightening protocolsespecially when oral or topical routes fall short

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