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[31] Disorders [edit] "Gluten-related disorders" is the umbrella term for all diseases triggered by gluten, which include celiac disease (CD), non-celiac gluten sensitivity (NCGS), wheat allergy, [32] gluten ataxia and dermatitis herpetiformis (DH)

It has also given plenty of scientific support for conditions such as nonalcoholic fatty liver disease, cardiovascular health problems and a host of different applications to neurodegenerative diseases from Alzheimer's Disease to Parkinson's

This permeating effect is secondary to the binding of specific undigestible gliadin fragments to the CXCR3 chemokine receptor with subsequent release of zonulin, a modulator of intercellular tight junctions

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However, with the addition of each tag comes the risk that the native function of the protein may be abolished or compromised by interactions with the tag