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The downregulation of OCTN2 activity and protein expression in the kidney reduces the reabsorption of carnitine in the kidney, leading to a decrease in carnitine availability in the liver and causing hepatic lipid metabolism disorders [260]

For anyone who is deficient in meats in their diet and wondering why the fat loss is difficult, Id recommend to try and supplement with a solid tri blend of Carnitine to see if it helps supplement your diet to aid in fat loss goals

2017 31:1_supplement, 802.5-802.5 [13] Raghubeer S, Matsha TE

Protein oxidation and aging