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Since ethanol caused a direct, unspecific, damage to the mucosa independent of GSH status (Table 1), the extent of injury in TNBS+ethanol-treated rats due to ethanol was subtracted to evaluate the injury due to the metabolism of TNBS

Support Care Cancer (2006) 14:113440.10.1007/s00520-006-0072-3 19 TurtleMJCullenPPrys-RobertsCCoatesDMonkCRFaroquiMH

Although GHRH-R couples with the G s protein, the addition of MK-0677 to rat primary cultured pituitary cells increased intracellular Ca 2+ levels, suggesting the existence of a second G protein-coupled receptor (GPCR) that couples with the G q protein, thereby promoting GH secretion through a pathway distinct from that of GHRH-R (Patchett et al., 1995)

Interestingly, vitamin C also functions as a pro-oxidant under certain circumstances

Neutralizes free radicals within the body