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Lewy bodies and -synuclein accumulation in the SN are hallmarks of the neuropathology of PD

Diabetes Care 35 , 731737 (2012)

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Three mitigation methods are commonly used: Chemical treatment

Conversely, taxa enriched in PD, such as members of the Enterobacteriaceae family, Akkermansia, and Desulfovibrio, are associated with heightened lipopolysaccharide burden, mucin degradation, and increased generation of reactive oxygen species, collectively amplifying innate immune activation and pro-inflammatory cascades