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TECs, central to both injury sensing and myofibroblast generation (197), initiate fibrogenic signaling, while myofibroblasts execute matrix accumulation (198)

In patients with vasospastic angina (n = 22, age 4164), L-citrulline supplementation (0.8 g/d, 48 weeks) increases brachial artery flow-mediated dilation, plasma NOx levels, and L-arginine/ADMA ratio (Morita et al., 2013)

10.1042/bj0150286 Biochem J

Drug interventions targeting the changing metabolic pathways in IDH1 mutations may suggest new treatment options for gliomas

This is particularly powerful for patients who are overweight and experiencing severe trouble losing weight with other interventions