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Extracellular superoxide dismutase (SOD), cytosolic copper, zinc SOD, and mitochondrially located manganese SOD (MnSOD) play a major role in the formation of hydrogen peroxide, whereas glutathione peroxidases (GPxs), catalase, and peroxiredoxins all play a role in the enzymatic catabolism of this ROS

10.1016/j.freeradbiomed.2013.07.042 274 ToulorgeD.GuerreiroS.HildA.MaskosU.HirschE