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FIGURE 1 6 Key priorities for clinical transformation 6.1 Precise patient stratification based on metabolic classification Combined imagingmulti-omics markers can identify metabolic subtypes, such as high glycolysis/low lipid-droplet load (including DCCD)/glutamine dependence, which inform cohort stratification and efficacy prediction

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Schttler S, Becker G, Winzen S, Steinbach T, Mohr K, Landfester K, Mailnder V, Wurm FR (2016) Protein adsorption is required for stealth effect of poly(ethylene glycol)- and poly(phosphoester)-coated nanocarriers