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Notably, it was recently shown that GSH induces features of trained immunity in human cells, via an unresolved mechanism [39]

A randomized double-blind placebo-controlled clinical trial, conducted among migraine patients, showed that CoQ10 supplementation at a dose of 400 mg/day for 3 months resulted in lower severity, duration, and frequency of headaches

[DOI] [PMC free article] [PubMed] [Google Scholar] 78.Gaston B, Reilly J, Drazen JM, Fackler J, Ramdev P, Arnelle D, Mullins ME, Sugarbaker DJ, Chee C, Singel DJ, Loscalzo J, Stamler JS