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Deficiency of thiosulfate sulfurtransferase mediates the dysfunction of renal tubular mitochondrial fatty acid oxidation in diabetic kidney disease

It is the single most protective antioxidant produced by the body and therefore the most important, as it protects cells against oxidative stress from free radicals

Zhang S, Xin W, Anderson GJ, Li R, Gao L, Chen S

Most notably, CDNF exhibits a targeted action profile: it affects only injured and stressed cells, sparing healthy neurons [82], which minimizes potential off-target effects