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Manganese superoxide dismutase (MnSOD) is an enzyme belonging to SOD, which is located in the mitochondrial matrix and can remove O 2 generated by energy metabolism, while glutathione peroxidase 1 (GPX1) is the most abundant of the four identified GPX isozymes

Among all cancers, digestive system malignant tumors (DSMTs) have the highest incidence and mortality rates, and the current therapeutic strategies for DSMTs are mainly surgical resection and chemotherapy

Expressions of oncogenic proteins phospho-Akt and SIRT1 were decreased

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Inhibition of silent information regulator 1 induces glucose metabolism disorders of hepatocytes and enhances hepatitis C virus replication