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4 Witschi A, Reddy S, Stofer B, Lauterburg B: The systemic availability of oral glutathione

10.1038/onc.2015.32 Oncogene 100 TangS.WangY.MaT.LuS.HuangK.LiQ

Further experiments have demonstrated that the peptide is capable of suppressing the activity of pro-inflammatory and fibrotic factors characteristic of the senescence-associated secretory phenotype (SASP), thereby contributing to the restoration of damaged tissue microenvironments

Histones including H1, H2A, H2B, H3 and H4 are known positively charged proteins which can bind tightly to the negatively charged DNA, favoring histone-DNA complex formation (also named nucleosome) [61]