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607 Upon LPS stimulation, activated macrophages undergo metabolic reprogramming, shifting from oxidative phosphorylation to glycolysis for ATP production, accompanied by the accumulation and oxidation of succinate

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This remarkable efficiency allows them to: Remove waste products from blood, including those from food, medications, and normal cell activity Balance fluids and electrolytes in your body Regulate blood pressure and pH levels Eliminate water-soluble toxins through urine Supporting Cast: Intestines, Skin, and Lungs While the liver and kidneys do the heavy lifting, other organs play important supporting roles: Intestines eliminate solid waste and prevent certain toxins from being absorbed Lungs expel gaseous waste products when we exhale Skin eliminates some waste products through sweat This integrated system works continuously to keep your body in balance

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