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Work Cited: Bahardoust, M., Aghakhani, Z., Mousavi, S., Donyadideh, G., Ziafati, H., Alipour, H., Haghmoradi, M., Olamaeian, F., Tayebi, A., & Tizmaghz, A

Studies suggest retinol's mechanism may involve modulation of pathways such as TGF- and mTOR signaling to counteract the senescence-associated secretory pattern (SASP)

DNA methylation can reduce gene expression by inhibiting transcription factor binding and potentially affecting nucleosome occupancy, together resulting in less accessible chromatin 21

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Glutamine, which is a nonessential amino acid (NEAA) due to the endogenous glutamine biosynthesis pathway, is currently considered essential in cancer cells because transformed cells consume glutamine at a rate exceeding that of glutamine biosynthesis 5