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Anabolic steroids, however, are often used for short-term, dramatic results and can pose significant long-term health risks

10.1016/j.molcel.2018.07.017 Mol

Wright C, Milne S, Leeson H

Note that caspase-8 is only secondarily activated as a consequence of lysosomal membrane permeabilization, which is caused by curcumin binding [44] and occurs upstream of ER membrane damage