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The URB597RSL3 combination targets both, reducing RCC cell viability via ferroptosis and G1 cell cycle arrest and exerting stronger effects on ferroptosis-related genes, proliferation, and invasion than single agents (264)

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However, subsequent well-designed, randomized, placebo-controlled clinical trials with NAC 600 mg three times daily, combined with other medications or in monotherapy failed to provide evidence supporting the use of NAC in patients with IPF [31] and identified safety issues with the combination of prednisone, azathioprine, and NAC [30]

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Wound healing benefits appear quickly but only in the context of active injuries or recovery