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In the dermato-aesthetic field, cycles of GSH IV combined with vitamin C show results on skin tone and reduction of hyperpigmentation, albeit in the absence of formal dedicated RCTs. Protocols and outcome assessment Currently used protocols for NAD IV involve doses of 250-500 mg per session, with slow infusions (2-6 hours) and weekly frequency for 4-8 weeks, followed by monthly maintenance

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Stepwise emergence of azole, echinocandin and amphotericin B multidrug resistance in vivo in Candida albicans orchestrated by multiple genetic alterations