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doi: 10.1038/nrclinonc.2018.29 130 LuoBZhangSTanDYuXLinJWangM

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On the other hand, mitochondrial dynamic imbalanceparticularly excessive fission-induced mitochondrial fragmentationinterferes with autophagic clearance of damaged mitochondria via mechanisms such as Drp1-Ser616 phosphorylation, identified as a key driver of apoptosis in ischemic myocardial injury