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Fishers exact, Chi-square, and Kruskal-Wallis tests were utilized to make comparisons between eras, with p 3cm (22% vs 5%

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More recently, it has been demonstrated that NSC-34 cells expressing TDP-43 mutants also exhibit shortened neurites, increased OS, and decreased HO1 level, and these effects can be reversed by the UPS inhibitor MG132, but not by the Nrf2 activator sulforaphane [255, 256], probably because MG132 induction of HO1 is Nrf2 independent