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Other studies have suggested that VNS may induce the release of ACh in the celiac mesenteric ganglia, which binds to post-synaptic 7nAChRs in the splenic nerve, releasing NE in the spleen to exert anti-inflammatory effects (108)

[DOI] [PubMed] [Google Scholar] 384.Wlodarczyk A, Grot D, Stoczynska-Fidelus E, Rieske P

doi: 10.1007/s00394-018-1876-x 100 KhorsandiHNikpayamOYousefiRParandooshMHosseinzadehNSaidpourAet al

Studies have displayed that in individuals with digestive imbalances, serum concentrations of collagen are decreased

Breast and ovarian tumor cells have higher IR expression relative to normal epithelial cells [38, 39] and patients with very high IR expression have worse disease free survival [40]