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10.1016/j.cell.2019.09.001 92 LuoY.SmithJ

This plasmid vector encodes antibiotic resistance (Ampr), a bacterial origin of replication (ori), an IPTG-regulatable promoter/operator (P/O), a ribosome binding site (RBS), a 6-histidine tag (6-His), and restriction enzyme cloning sites

But the speculators appealed all the way to the U.S